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DR. NICHOLAS P. RHODES
The BBC article
Human blood vessels grown in mice said
Scientists have used human cells to grow new blood vessels in a mouse
for the first time.
It could eventually help patients who had suffered heart attacks, they
said.
A mixture of "progenitor" cells, taken from blood and bone marrow, made
cells lining the vessels, and also those surrounding the
lining.
Dr Nick Rhodes, from the UK Centre for Tissue Engineering at the
University of Liverpool, said that the results were "interesting and
promising".
He said: "It could certainly assist in the connection of other
engineered organs to the body's blood supply.
Nicholas P. Rhodes, B.Sc., M.Sc., Ph.D. is Reader in Tissue
Engineering &
Regenerative Medicine, University of Liverpool.
Nick's active research projects include:
STEPS: A Systems Approach to Tissue Engineering Processes and
Products. This program
is an integrated project under the FP6 aiming to successfully implement
TE, systematically linking together all aspects of this
multi-disciplinary process by applying the logistics of systems
engineering, providing a totally new infrastructure.
Specifically, the technological components will include cell sourcing
and manipulation, novel biomaterial development, bioreactor design, and
the integration of TE constructs into the living host.
REMEDI: Regenerative medicine — a new industry. This program's
main aim is to demonstrate how established bio-science can be
transformed into profitable commercial practice and generate affordable
therapies while developing the science of manufacture. The main tasks
include:
- Determining the value of tissue engineered products to users in
healthcare, thus defining the market place and showing how the
development of regulation and industrial policy can maximize economic
benefit while protecting patients.
- Creating and demonstrating reproducible cost effective processes
for the scaleable production of cells, scaffolds, and tissue products
that satisfy the regulator and take advantage of emerging sensing and
control techniques.
- Constructing a community that integrates the Challenge
program
and generates a shared vision for the industry and its future products
and explores these visions practically. He is developing techniques
to
enable life science and manufacturing professionals in SMEs to create
cost effective manufacturing systems, pre-clinically, while managing
biological risk.
Nick authored
Inflammatory signals in the development of
tissue-engineered soft tissue
and coauthored
Analysis of the cellular infiltration of benzyl-esterified hyaluronan
sponges implanted in rats,
Induction of adipose tissue regeneration by chemically-modified
hyaluronic acid,
The effect of gas plasma modification on platelet and contact phase
activation processes,
Autologous in vivo tissue engineering in hyaluronan-based gels
— a
pilot
study,
Control of the domain microstructures of PLGA and PCL binary systems:
Importance of morphology in controlled drug release, and
Effect of titanium carbide coating on the osseointegration response
in
vitro and in vivo.
Listen to Nick on
Regenerative
Medicine Today.
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